A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
167/260
A61K 31/195 (2006.01) A61K 9/00 (2006.01) A61K 31/60 (2006.01) A61K 47/02 (2006.01) A61K 47/18 (2006.01) A61K 47/22 (2006.01)
Patent
CA 2016825
Abstract of the Disclosure An aqueous solution of 5-aminosalicylic acid (5-ASA) and a nontoxic alkali, alkali metal or alkaline earth metal salt of 5-aminosalicylic acid having a pH of 3-5 is dis- closed. The sole buffer in the solution is that intrinsic- ally formed by 5-aminosalicylic acid and its alkali, alkali metal or alkaline earth metal salt. The solutions prefer- ably also contain an antioxidant and a metal complexing agent. In preferred practice, the 5-ASA salt is formed in situ by addition of an alkali, alkali metal or alkaline earth metal hydroxide to a solution of 5-ASA. The solution is stable and does not significantly discolor due to 5-ASA decomposition for extended periods of time. MO1529
Bottom Carey B.
Kwoka Margaret N.
Marion Merrell Dow Inc.
Osler Hoskin & Harcourt Llp
LandOfFree
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