Pharmaceutical compositions

Details Pharmaceutical compositions Pharmaceutical compositions

A - Human Necessities

61

K

A61K 31/70 (2006.01) A61P 3/10 (2006.01)

Patent

CA 2755392

A pharmaceutical composition comprising a combination of (A) a 1-thio-D- glucitol compound represented by the general formula (I) and (B) at least one member of the group consisting of biguanides, insulin secretagogues, insulin sensitizers, insulins, dipeptidyl peptidase IV inhibitors, .alpha.-glucosidase inhibitors, and GLP-1 mimetics, has superior efficacy in preventing or treating diabetes mellitus, diseases associated with diabetes mellitus, or complications of diabetes mellitus and yet it causes no ap-preciable side effects.

L'invention porte sur une composition pharmaceutique comprenant une combinaison de (A) un composé 1-thio-D-glucitol représenté par la formule générale (I) et (B) au moins un élément du groupe constitué par les biguanides, les sécrétagogues de l'insuline, les agents de sensibilisation à l'insuline, les insulines, les inhibiteurs de dipeptidyl peptidase IV, les inhibiteurs d'a-glucosidase et les mimétiques de GLP-1. La composition pharmaceutique a une efficacité supérieure pour la prévention ou le traitement du diabète sucré, de maladies associées au diabète sucré, ou de complications du diabète sucré, mais n'a cependant pas d'effets secondaires à signaler.

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