Recombinant mersacidin and a method for production

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/31 (2006.01) A61K 38/16 (2006.01) C07K 14/32 (2006.01) C12N 1/21 (2006.01) C12N 15/63 (2006.01) C12P 21/02 (2006.01) C07K 7/56 (2006.01)

Patent

CA 2157975

The present invention refers in particular to the structural gene sequence of the peptide antibiotic mersacidin. Sequencing revealed that premersacidin consists of an unusually long 48 amino acid leader sequence and a 20 amino acid propeptide part which is modified during biosynthesis to the mature lantibiotic.

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