C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) C07H 21/00 (2006.01) C07K 14/705 (2006.01) C12Q 1/68 (2006.01) G01N 33/566 (2006.01)
Patent
CA 2265485
This invention relates to small and intermediate conductance, calcium- activated potassium channel proteins. More specifically, the invention relates to compositions and methods for making and detecting calcium- activated potassium channel proteins and the nucleic acids encoding calcium-activated potassium channel proteins. The invention also provides methods and compositons for assaying compounds which increase or decrease potassium ion flux through a calcium-activated potassium channel.
L'invention a pour objet des protéines de canal potassium à basse et moyenne conductance, activées par le calcium. L'invention se rapporte plus particulièrement à des méthodes et des compositions permettant de fabriquer et de détecter des protéines de canal potassium activées par le calcium ainsi que les acides nucléiques codant des protéines de canal potassium activées par le calcium. L'invention concerne également des méthodes et des compositions permettant d'analyser des composés qui augmentent ou réduisent le flux d'ions potassium dans un canal potassium activé par le calcium.
Adelman John P.
Bond Chris T.
Maylie James
Silvia Christopher P.
Icagen Inc.
Oregon Health Sciences University
Smart & Biggar
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