C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 39/35 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/435 (2006.01) C07K 14/725 (2006.01) C07K 16/18 (2006.01) C12N 5/10 (2006.01) G01N 33/564 (2006.01) G01N 33/566 (2006.01) G01N 33/569 (2006.01) G01N 33/577 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01) A61K 38/11 (2006.01) C12N 5/08 (2006.01)
Patent
CA 2158047
Isolated nucleic acids encoding allergens of the species Dermatophagoides farinae, Der p VII and Der f VII, respectively, are disclosed. A cDNA encoding a peptide having a Der p VII activity and a predicted molecular weight of about 22,177 daltons is described. A cDNA encoding a peptide having Der f VII activity is also described. The nucleic acids of the invention can be used as probes to detect the presence of Der p VII of Der f VII nucleic acid in a sample or for the recombinant production of peptides having a Der p VII or Der f VII activity. Peptides having a Der p VII or Der f VII activity can be used in compositions suitable for pharmaceutical administration or methods of diagnosing sensitivity of house dust mite allergens.
Chua Kaw-Yan
Thomas Wayne Robert
Institute For Child Health Research
Smart & Biggar
LandOfFree
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