Gel bases for pharmaceutical compositions

A - Human Necessities – 61 – K

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A61K 9/00 (2006.01) A61K 47/10 (2006.01)

Patent

CA 2000837

ABSTRACT Gel bases for pharmaceutical compositions comprise from about 0.5 to about 10.0% by weight ethoxylated (2 to 30 moles of ethocylation) behenyl alcohol and from about 90 to 99.5% of a glycol solvent or from about 2.5 to about 10.0% by weight ethoxylated fatty alcohols having a chain length or from 16 to 21 carbon atoms and from 90 to about 97.5% of a glycol solvent. Preferred glycol solvents include propylene glycol and polyethylene glycols having an average molecular weight of about 200 to 800. Pharmaceutical compositions suitable for topical, transmucosal and oral administration may be prepared utilizing the novel gel bases. Methods of administration of topically, systemically and orally active pharmaceutical agents utilizing the novel gel bases are also provided.

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