Multicomponent immunogenic composition for the prevention of...

C - Chemistry – Metallurgy – 07 – K

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C07K 14/315 (2006.01) C07K 16/12 (2006.01)

Patent

CA 2741691

A number of .beta.-hemolytic streptococci polynucleotides and polypeptides, particularly Streptococcus pyogenes polypeptides and polynucleotides, are described. Two or more of the polypeptides of the invention can be formulated for use as immunogenic compositions. Also disclosed are methods for immunizing against and reducing infection caused by .beta. -hemolytic streptococci.

L'invention porte sur un nombre de polynucléotides et polypeptides de streptocoques ß-hémolytiques, en particulier sur des polypeptides et des polynucléotides de Streptococcus pyogenes. Au moins deux des polypeptides de l'invention peuvent être formulés pour une utilisation en tant que compositions immunogènes. L'invention porte également sur des procédés d'immunisation contre une infection provoquée par des streptocoques ß-hémolytiques, ou sa réduction.

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