Activators and therapeutic applications thereof

Details Activators and therapeutic applications thereof Activators and therapeutic applications thereof

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/381 (2006.01) A61K 31/4162 (2006.01) A61K 31/4196 (2006.01) A61K 31/4375 (2006.01) A61K 31/498 (2006.01) A61K 31/4985 (2006.01) A61P 35/00 (2006.01) C07D 215/46 (2006.01) C07D 239/88 (2006.01) C07D 487/04 (2006.01) C07D 495/14 (2006.01)

Patent

CA 2691227

The invention presents methods of identifying small molecule compounds that are activators of tumor suppressor protein p53 pathway, and its associated family members p63 and p73, function. The invention is further drawn to methods of killing tumor cells and treating cancers or other conditions requiring activation of the p53 family member pathways and DNA damage response pathways with the small molecules.

La présente invention concerne des procédés d'identification de composés de petites molécules qui sont des activateurs de la voie de la protéine p53 de suppression de la tumeur, et des éléments p63 et p73 de la famille qui lui sont associés. L'invention concerne en outre des procédés consistant à tuer des cellules tumorales et à traiter les cancers ou autres conditions nécessitant l'activation des voies d'un élément de la famille de p53 et des voies de réponse à un dommage de l'ADN avec les petites molécules.

Affiliated with

Also associated with

Rating

Activators and therapeutic applications thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Activators and therapeutic applications thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Activators and therapeutic applications thereof will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1613669