Taxane based compositions and methods of use

Details Taxane based compositions and methods of use Taxane based compositions and methods of use

A - Human Necessities

61

K

A61K 31/337 (2006.01) A61K 31/33 (2006.01) A61K 47/10 (2006.01) A61K 47/22 (2006.01)

Patent

CA 2471572

Disclosed are taxane-based compostions and methods of using the same to achieve target blood levels of a taxane in a mammal, e.g., to treat taxane- responsive malignant and non-malignant diseases. Compositions of the invention exhibit long-term stability and overall palatability. Also disclosed are methods for using the compositions as analytical tools for pharmacokinetic studies.

L'invention concerne des compositions à base de taxane et des procédés d'utilisation de ces dernières pour atteindre des niveaux sanguins cibles de taxane chez un mammifère, par exemple, pour traiter les maladies malignes et non malignes répondant à la taxane. L'invention traite de compositions qui présentent une stabilité à long terme et une appétibilité globale. L'invention a aussi pour objet des procédés d'utilisation des compositions comme outils analytiques pour réaliser des études pharmacocinétiques.

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