Ischemic biomarkers and their use to predict adverse...

Details Ischemic biomarkers and their use to predict adverse... Ischemic biomarkers and their use to predict adverse...

G - Physics

01

N

G01N 33/53 (2006.01) G01N 33/537 (2006.01) G01N 33/543 (2006.01) G01N 33/566 (2006.01)

Patent

CA 2595263

Methods are provided for predicting the occurrence of adverse neurological events from surgery. Such adverse events include, for example, stroke, delirium and transient ischemic attach (TIA). The methods are based on the discovery that levels of circulating cerebral NMDA receptor peptides and antibodies can be used to identify patients who are likely to suffer from an adverse neurological event. Also provided are diagnostic procedures for practicing the predictve methods of the current invention, and interventional strategies for reducing the risk of adverse neurological events from surgery (Figure 1).

L'invention porte sur des procédés permettant de prévoir l'apparition d'événements neurologiques indésirables dus à une intervention chirurgicale. Parmi ces événements indésirables figurent par exemple les attaques, les délires et les accidents ischémiques transitoires. Ces procédés sont fondés sur la découverte selon laquelle les niveaux de peptides du récepteur de NMDA cérébral circulant et les niveaux des anticorps peuvent servir à identifier des patients susceptibles de souffrir d'un événement neurologique indésirable. L'invention porte sur des procédures diagnostiques permettant de mettre en oeuvre ces procédés de prévision, ainsi que des stratégies d'intervention afin de réduire le risque d'événements neurologiques indésirables dus à une intervention chirurgicale.

Affiliated with

Also associated with

Rating

Ischemic biomarkers and their use to predict adverse... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Ischemic biomarkers and their use to predict adverse..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Ischemic biomarkers and their use to predict adverse... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1614095