Novel compounds

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 235/06 (2006.01) A61K 31/4184 (2006.01) A61K 31/4439 (2006.01) A61P 25/04 (2006.01) A61P 25/16 (2006.01) A61P 35/00 (2006.01) C07D 235/12 (2006.01) C07D 401/06 (2006.01) C07D 401/14 (2006.01) C07D 403/06 (2006.01) C07D 405/06 (2006.01) C07D 405/14 (2006.01) C07D 413/06 (2006.01) C07D 413/14 (2006.01)

Patent

CA 2501418

Compounds of formula (I) wherein R<SP>F1</SP>, R<SP>F2</SP>, Z, R1, R2, Ar, X and Y are as defined in the specification as well as salts and pharmaceutical compositions including the compounds were prepared. These compounds are useful in therapy, in particular in the management of pain.

La présente invention concerne des composés représentés par la formule générale (I) ainsi que certains de leurs sels et les compositions pharmaceutiques les intégrant. Dans cette formule (I), R<SP>F1</SP>, R<SP>F2</SP>, Z, R?1¿, R?2¿, Ar, X et Y sont tels que décrits dans les spécifications. Ces composés conviennent à des fins thérapeutiques, notamment pour le contrôle de la douleur.

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