4-piperazinyl-pyrimidine compounds suitable for treating...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 417/12 (2006.01) A61K 31/505 (2006.01) A61K 31/506 (2006.01) A61P 25/16 (2006.01) A61P 25/18 (2006.01) A61P 25/24 (2006.01) C07D 239/42 (2006.01) C07D 239/52 (2006.01) C07D 239/56 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01)

Patent

CA 2574827

The present invention relates to novel 4-piperazinylpyrimidine compounds. The compounds possess valuable therapeutic properties and are suitable, in particular, for treating diseases that respond to modulation of the dopamine D3 receptor. The 4~ piperzinylpyrimidine compounds have the general formula (I), wherein Ar, X, A, R1 and R1a are as defined in the claims.

La présente invention concerne des composés de 4-pipérazinylpyrimidine. Les composés possèdent de précieuses propriétés thérapeutiques et conviennent, en particulier, pour traiter des maladies qui répondent à une modulation du récepteur D3 de la dopamine. Les composés de 4-pipérazinylpyrimidine ont la formule générale (I), dans laquelle Ar, X, A, R1 et R1a sont tels que définis dans les revendications.

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