Inhibitors of checkpoint kinases

Details Inhibitors of checkpoint kinases Inhibitors of checkpoint kinases

C - Chemistry, Metallurgy

07

D

C07D 471/14 (2006.01) A61K 31/437 (2006.01) A61K 31/4375 (2006.01) C07D 471/16 (2006.01)

Patent

CA 2614257

The instant invention provides for compounds which comprise fused imidazoles that inhibit CHK1 activity. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting CHK1 activity by administering the compound to a patient in need of treatment of cancer.

La présente invention a pour objet des composés qui comprennent des imidazoles fusionnés qui inhibent l'activité de CHK1. L'invention concerne aussi des compositions qui comprennent de tels composés inhibiteurs et des méthodes pour inhiber l'activité de CHK1 en administrant le composé à un patient nécessitant un traitement du cancer.

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