Polymer formulations of cetp inhibitors

Details Polymer formulations of cetp inhibitors Polymer formulations of cetp inhibitors

A - Human Necessities

61

K

A61K 9/16 (2006.01) A61K 9/20 (2006.01)

Patent

CA 2641451

A pharmaceutical composition comprises (a) a CETP inhibiting compound, or a pharmaceutically acceptable salt thereof; (b) a concentration-enhancing polymer; and (c) optionally one or more surfactants; wherein the compound has the structure shown as Formula I below. The composition raises HDL-cholesterol and lowers LDL-cholesterol.

La présente invention concerne une composition pharmaceutique comprenant (a) un composé d'inhibition de CETP, ou sel dérivé pharmaceutiquement acceptable, (b) un polymère d'amélioration de concentration et (c), en option, au moins un tensioactif, sachant que le composé a la structure affichée dans la Formule I ci-dessous. La composition augmente le cholestérol HDL et diminue le cholestérol LDL.

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