Use of pkc inhibitors for the manufacture of a medicament...

Details Use of pkc inhibitors for the manufacture of a medicament... Use of pkc inhibitors for the manufacture of a medicament...

A - Human Necessities

61

K

A61K 31/40 (2006.01) A61K 31/00 (2006.01) A61K 31/555 (2006.01)

Patent

CA 2323158

A method for treating CMV infection and disease conditions associated therewith is disclosed, particularly using the isozyme selective PKC inhibitor, (S)-3,4-[N,N'-1,1'-((2"-ethoxy)-3'''(O)-4'''-(N,N-dimethylamino)- butane)-bis-(3,3'-indoly1)]-1(H)-pyrrole-2,5-dione hydrochloride salt.

Cette invention se rapporte à un procédé pour traiter les infections à cytomégalovirus (CMV) et les états pathologiques associés à ces infections, notamment en utilisant l'inhibiteur de protéine-kinase C (PKC) à sélectivité pour les isozymes, à savoir le sel hydrochlorure de (S)-3,4-[N,N'-1,1'-((2''-éthoxy)-3'''(O)-4'''-(N,N-diméthylamino)-butane)-bis-(3-3'-indolyl)]-1(H)-pyrrole-2,5-dione.

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