Novel carboxylic acid derivatives, their preparation and use...

Details Novel carboxylic acid derivatives, their preparation and use... Novel carboxylic acid derivatives, their preparation and use...

A - Human Necessities

61

K

A61K 31/505 (2006.01) A61K 31/506 (2006.01) A61K 31/517 (2006.01) A61K 31/519 (2006.01) A61K 31/53 (2006.01)

Patent

CA 2283732

This invention provides a method for treating cancer in an individual, wherein the cancer is a tumor in which endothelin is upregulated (e.g. tumors of the prostate, lung, liver, breast, brain, stomach, colon, endometrium, testicle, thyroid, pituitary, bladder, kidney, pancreas and meninges) by administering to the individual an effective amount of a compound of formula (I) or formula (Ia), as described therein.

L'invention concerne une méthode de traitement du cancer chez un individu, le cancer étant une tumeur dans laquelle l'endothéline est régulée de manière positive (telles les tumeurs de la prostate, du poumon, du foie, du sein, du cerveau, de l'estomac, du colon, de l'endométrium, des testicules, de la thyroïde, de l'hypophyse, de la vessie, du rein, du pancréas et des méninges) par l'administration à l'individu d'une dose efficace d'un composé de formule (I) ou de formule (Ia), conformément à la description.

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