Increase of immune response and targeting by antigens and/or...

Details Increase of immune response and targeting by antigens and/or... Increase of immune response and targeting by antigens and/or...

A - Human Necessities

61

K

A61K 47/48 (2006.01) A61K 39/385 (2006.01) C07H 15/06 (2006.01)

Patent

CA 2705067

The present invention relates to compounds consisting of glycolipids covalently bound to an antigen or a drug via a linker. The said compounds are able to induce a stronger immune response than a composition comprising separated glycolipids and antigen. The said compounds are also able to target drug to CD1d restricted cells.

La présente invention porte sur des composés consistant en des glycolipides liés de manière covalente à un antigène ou à un médicament par l'intermédiaire d'un liant. Lesdits composés sont aptes à induire une réponse immunitaire plus forte qu'une composition comprenant des glycolipides et un antigène séparés. Lesdits composés sont également aptes à cibler un médicament vers des cellules à CD1d-restreintes.

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