Small molecule inhibitors of pdz interactions

Details Small molecule inhibitors of pdz interactions Small molecule inhibitors of pdz interactions

A - Human Necessities

61

K

A61K 31/192 (2006.01) A61K 31/436 (2006.01) A61P 9/10 (2006.01) A61P 25/04 (2006.01)

Patent

CA 2641421

The present invention relates to compositions for use in the modulation of PDZ domain interactions with cognate ligands. Methods of assessing and characterizing PDZ domain interactions from various polypeptides also are provided.

La présente invention concerne des compositions utilisées pour moduler les interactions entre le domaine PDZ et des ligands apparentés. La présente invention concerne également de procédés d~évaluation et de caractérisation des interactions du domaine PDZ à partir de différents polypeptides.

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