Nucleic acid probes useful fo the detection of mycobacterium...

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/68 (2006.01) C07H 21/00 (2006.01) C07K 14/22 (2006.01) C07K 14/35 (2006.01)

Patent

CA 2106869

2106869 9216652 PCTABS00016 A method for detecting the presence of M. tuberculosis in a biological sample is provided, comprising the steps of: (a) treating cells contained within the biological sample to expose cellular nucleic acids; (b) incubating the cellular nucleic acids with a labeled M. tuberculosis specific probe under conditions and for a time sufficient for hybridization to occur; and (c) detecting the presence of the hybridized, labeled M. tuberculosis specific probe. Also provided within this invention is a polypeptide derived from M. tuberculosis.

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