Indoline-sulfanilic acid amides used as ppar delta modulators

Details Indoline-sulfanilic acid amides used as ppar delta modulators Indoline-sulfanilic acid amides used as ppar delta modulators

A - Human Necessities

61

K

A61K 31/404 (2006.01) A61P 3/06 (2006.01) A61P 9/10 (2006.01) C07D 209/08 (2006.01) C07D 209/96 (2006.01)

Patent

CA 2534194

The invention relates to novel indolin-sulfanilic acid amides of general formula (I), methods for the production thereof, and the use thereof in medicaments, especially as potent PPAR delta agonists for preventing and/or treating cardiovascular diseases, particularly dyslipidemia, arteriosclerosis, and coronary heart diseases.

L'invention concerne de nouveaux amides d'acide indolino-sulfanilique de la formule générale (I), leur procédé de production ainsi que leur utilisation dans des médicaments, notamment comme composés potentiels activant le PPAR-delta, destinés à la prévention et/ou au traitement de maladies cardio-vasculaires, notamment de la dyslipidémie, de l'artériosclérose et de la cardiopathie ischémique.

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