Isolated, truncated nucleic acid molecules which code for...

Details Isolated, truncated nucleic acid molecules which code for... Isolated, truncated nucleic acid molecules which code for...

C - Chemistry, Metallurgy

07

K

C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C12Q 1/02 (2006.01) G01N 33/574 (2006.01) G01N 33/60 (2006.01)

Patent

CA 2210318

A new family of tumor rejection antigen precursors, and the nucleic acid molecules which code for them, are disclosed. These tumor rejection antigen precursors are referred to as GAGE tumor rejection antigen precursors, and the nucleic acid molecules which code for them are referred to as GAGE coding molecules. Various diagnostic and therapeutic uses of the coding sequences and the tumor rejection antigens, and their precursor molecules are described. Tumor rejection antigens are also shown.

L'invention porte sur une nouvelle famille de précurseurs d'antigènes de rejet des tumeurs et sur les molécules d'acide nucléique codant pour elles. Ces précurseurs d'antigène de rejet de tumeurs sont appelés précurseurs GAGE, et les molécules d'acide nucléique sont appelées molécules de codage de GAGE. L'invention porte également sur de nombreuses applications à caractère diagnostique et thérapeutique des séquences de codage et des antigènes de réjet des tumeurs, sur leurs molécules précurseurs, ainsi que sur les antigènes de rejet des tumeurs proprement dits.

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