C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/24 (2006.01) A01K 67/027 (2006.01) A61K 31/70 (2006.01) A61K 31/7088 (2006.01) A61K 38/20 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) A61P 37/02 (2006.01) C07H 21/00 (2006.01) C07K 14/54 (2006.01) C07K 16/18 (2006.01) C12N 5/10 (2006.01) C12N 15/11 (2006.01) C12N 15/62 (2006.01) C12N 15/63 (2006.01) C12P 21/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01) G01N 33/566 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2521331
The present invention discloses open reading frames (ORFs) in human genome encoding for novel IL-8-like/TMEM9 polypeptides, and reagents related thereto including variants, mutants and fragments of said polypeptides, as well as ligands and antagonists directed against them. The invention provides methods for identifying and making these molecules, for preparing pharmaceutical compositions containing them, and for using them in the diagnosis, prevention and treatment of diseases.
La présente invention concerne des cadres de lecture ouverts (ORF) dans le génome humain codant pour de nouveaux polypeptides de type IL-8/TMEM9, ainsi que les réactifs associés, y compris des variants, des mutants et des fragments desdits polypeptides, ainsi que des ligands et des antagonistes contre eux. L'invention présente des méthodes d'identification et de production de ces molécules pour la préparation de compositions pharmaceutiques les contenant, et pour leur utilisation dans le diagnostic, la prévention et le traitement de pathologies.
Bienkowska Jadwiga
Gorski Regina
Mcallister Gregg
Applied Research Systems Ars Holding N.v.
Kirby Eades Gale Baker
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