Methods for treating and diagnosing complications of...

A - Human Necessities – 61 – K

Patent

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A61K 31/56 (2006.01)

Patent

CA 2614677

Methods and compositions for treating and/or preventing complications of preterm birth are provided. The methods involve administration of 2- methoxyestradiol, or an analog thereof, to a subject. Also provided are methods for diagnosing or predicting complications of preterm birth. The methods involve detection of 2- methoxyestradiol, or a precursor or metabolite thereof.

L'invention concerne des méthodes et des compositions permettant de traiter et/ou de prévenir des complications dans une naissance prématurée. Lesdites méthodes impliquent l'administration de 2-méthoxyestradiol ou d'un analogue de celui-ci à un sujet. L'invention concerne également des méthodes permettant de diagnostiquer ou de prédire des complications dans une naissance prématurée. Ces méthodes impliquent la détection de 2-méthoxyestradiol ou d'un précurseur ou d'un métabolite de celui-ci.

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