Method of measuring platelet activation

Details Method of measuring platelet activation Method of measuring platelet activation

G - Physics

01

N

G01N 33/86 (2006.01)

Patent

CA 2428224

Platelet activation is measured by determining Mean Platelet Component (MPC) of suspended blood platelets, using a specific anticoagulant composition. The composition comprises at least one component for effecting platelet sphering (for example EDTA), and at least one platelet antagonist (for example at least one of, and preferably all three of theophylline, adenosine and dipyridamole).

L'invention concerne l'activation des plaquettes mesurée par détermination d'un composant moyen de plaquette (MCP) de plaquettes sanguines suspendues, au moyen d'une composition anticoagulante spécifique. Cette composition comprend au moins un composé permettant la mise en forme sphérique d'une plaquette (par exemple EDTA) et au moins un antagoniste de plaquette (par exemple au moins une parmi les trois substances, et de préférence les trois substances: théophylline, adénosine et dipyridamole).

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