A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 49/00 (2006.01) C08B 37/00 (2006.01)
Patent
CA 2101267
A process is described for the production of a readily water-soluble fructan as well as a well-tolerated renal diagnostic agent containing such a fructan. In the process an aqueous fructan extract obtained from parts of plants is ultrafiltered over a first membrane which retains carbohydrates and proteins with a higher molecular weight but which allows passage of fructan and the filtrate obtained in this way is then filtered in a second ultrafiltration through a membrane which retains fructan but which allows passage of salts and low-molecular substances such as monosaccharides and oligosaccharides. The fructan obtained in this way is used as a renal diagnostic agent together with physiologically tolerated buffer substances at an osmolality which corresponds to that of blood and which has a pH of 5.0 to 7Ø
Méthode de production d'un fructosane très hydrosoluble et d'un agent bien toléré pour le diagnostic des troubles rénaux qui contient un tel fructosane. Dans cette méthode, un extrait de fructosane aqueux provenant de parties de plantes est passé par ultrafiltration à travers une première membrane qui retient les hydrates de carbone et les protéines de poids moléculaire plus élevé mais qui laisse passer le fructosane, et le filtrat ainsi obtenu est passé par ultrafiltration à travers une seconde membrane qui retient le fructosane mais laisse passer les sels et les substances de faible poids moléculaire telles qu les monosaccharides et les oligosaccharides. Le fructosane ainsi obtenu est utilisé comme agent pour le diagnostic des troubles rénaux en association avec des substances tampons bien tolérées physiologiquement dont le degré d'osmolalité correspond à celui du sang et dont le pH se situe entre 5,0 et 7Ø
Laevosan Gesellschaft Mbh
Swabey Ogilvy Renault
LandOfFree
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