A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/19 (2006.01) A61P 31/00 (2006.01) A61P 35/00 (2006.01) A61P 37/08 (2006.01)
Patent
CA 2632262
Disclosed are methods of treating an individual having a condition characterized by an imbalance in type (1) and type (2) cytokine production, wherein the method comprises administering to the individual an amount of &bgr; -hydroxy- &bgr; -me thylbutyrate (HMB) effective to modulate or otherwise cause an increase in the ratio of type (1) to type (2) cytokines, including an increase in the ratio of type (1) to type (2) cytokines without a corresponding increase in type (2) cytokine levels. Also disclosed are methods of using HMB to treat asthma, allergies and cancer. The methods of the present invention are based upon the discovery that HMB modulates cytokine production, most typically by increasing type (1) cytokines without a corresponding increase in type (2) cytokines.
L'invention concerne des méthodes de traitement d'un individu dont l'état se caractérise par un déséquilibre dans la production de cytokines de type (1) et de type (2), le procédé consistant à administrer à l'individu une quantité de ß-hydroxy-ß-methylbutyrate (HMB) efficace pour moduler ou permettre d'augmenter le ratio des cytokines de type (1) sur les cytokines de type (2), comprenant une augmentation dans le ratio des cytokines de type (1) sur les cytokines de type (2) sans augmentation correspondante des concentrations en cytokines de type (2). L'invention concerne également des procédés d'utilisation de HMB pour traiter l'asthme et les allergies. Les procédés selon l'invention reposent sur la découverte selon laquelle HMB module la production de cytokines, plus particulièrement en permettant d'augmenter les cytokines de type (1) sans augmenter simultanément les cytokines de type (2).
Mukerji Pradip
Thomas Debra L.
Abbott Laboratories
Mbm Intellectual Property Law Llp
LandOfFree
Use of beta-hydroxy-beta-methylbutyrate to modulate the... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Use of beta-hydroxy-beta-methylbutyrate to modulate the..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Use of beta-hydroxy-beta-methylbutyrate to modulate the... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1621642