C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/705 (2006.01) A61K 38/17 (2006.01) A61P 25/00 (2006.01) C12N 15/12 (2006.01) C12Q 1/68 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2405311
The present invention provides multi-protein complexes, and sub-complexes thereof, and methods of producing the same. Preferably, the complexes comprise an NMDA receptor. The present invention further provides methods of identifying a compound for treating disorders and conditions associated with dysfunction of NMDA receptors in the central nervous system. Additionally, there are provided methods of diagnosing or aiding diagnosis of disorders and conditions associated with dysfunction of NMDA receptors in the central nervous system.
L'invention concerne des complexes de multiples protéines et des sous-complexes de ceux-ci, ainsi que des procédés de production de ceux-ci. De préférence, les complexes contiennent un récepteur NMDA. L'invention concerne de plus des procédés visant à identifier un composé capable de traiter des troubles et des affections associés à un dysfonctionnement des récepteurs NMDA du système nerveux central. L'invention concerne en outre des procédés utiles au diagnostic ou pouvant faciliter le diagnostic de troubles et d'affections associés à un dysfonctionnement des récepteurs NMDA du système nerveux central.
Grant Seth Garran Niels
Husi Holger
Smart & Biggar
The University Court Of The University Of Edinburgh Incorporated
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