C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C07H 21/04 (2006.01) C07K 14/47 (2006.01) C12N 1/20 (2006.01) C12N 15/00 (2006.01) C12P 19/34 (2006.01)
Patent
CA 2300349
This invention provides a novel nucleic acid molecule, CLAR1, isolated from a human adult heart cDNA library. This cDNA is derived from a novel gene that represents a late stage-specific marker for prostate cancer progression. The CLAR1 cDNA, along with its encoded protein and antibodies thereto, provides a biological marker for aggressive prostate cancer.
L'invention concerne une nouvelle molécule d'acide nucléique, CLAR1, isolée d'une bibliothèque d'ADN complémentaire du coeur humain adulte. Cet ADNc provient d'un nouveau gène qui représente un marqueur spécifique d'un stade tardif dans l'évolution du cancer de la prostate. Le CLAR1 ADNc fournit, conjointement avec sa protéine codée et les anticorps associés, un marqueur biologique pour le cancer agressif de la prostate.
Rondinelli Rachel
Tricoli James V.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Fox Chase Cancer Center
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