Restoration of hearing loss

A - Human Necessities – 61 – K

Patent

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Details

A61K 48/00 (2006.01) A61K 31/7088 (2006.01) A61K 49/00 (2006.01) A61P 27/16 (2006.01) A61K 35/12 (2006.01)

Patent

CA 2655990

The present invention relates to compositions and methods for restoring hearing loss. In particular aspects, the invention relates to the administration of compositions that encode an inflammatory response control element. The compositions are prepared and administered in such a manner that the inflammatory response control element coding sequence is expressed in the subject to which the composition is administered. The compositions include expression systems, delivery systems, and certain inflammatory response control genes.

La présente invention concerne des compositions et des procédés permettant de corriger une perte auditive. Selon certains aspects particuliers, l'invention concerne l'administration de compositions codant un élément qui contrôle la réponse inflammatoire. Les compositions sont préparées et administrées de telle sorte que la séquence codant l'élément qui contrôle la réponse inflammatoire est exprimée chez le sujet auquel la composition est administrée. Les compositions comprennent des systèmes d'expression, des systèmes d'administration, et certains gènes qui contrôlent la réponse inflammatoire.

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