Nasal spray having dead sea salts

Details Nasal spray having dead sea salts Nasal spray having dead sea salts

A - Human Necessities

61

K

A61K 33/00 (2006.01) A61K 33/06 (2006.01) A61K 33/14 (2006.01)

Patent

CA 2377088

A nasal spray formulation for use with the treatment of rhinitis, sinusitis, epistaxis and post-surgical irrigation. The nasal spray formulation includes the Dead Sea salt or its equivalent. The composition of the Dead Sea salt mixture includes about 31-35 % magnesium halide, about 24-26 % potassium halide, about 4-8 % sodium halide, about 0.4-0.6 % calcium halide, the halide being about 0.3-0.6 % bromide, about 99.4-99.7 % chloride, and may also include about 0.05-0.2 % sulphates, about 0.5-0.2 % insolubles. The salts may comprise about 34-38 % water of crystallization. The spray formulation is about 0.5 to about 5 grams per liter of sterile aqueous solution, contains a buffer, and is essentially free of noxious, organic impurities.

L'invention concerne une formulation d'aérosol nasal destinée à être utilisée pour le traitement de la rhinite, de la sinusite, de l'épistaxis et de l'irrigation post-chirurgicale. Cette formulation d'aérosol nasal renferme du sel de la Mer morte ou son équivalent. La composition du mélange de sels de la Mer morte comprend 31-35 % environ d'halogénure de magnésium, 24-26 % environ d'halogénure de potassium, 4-8 % environ d'halogénure de sodium, 0,4-0,6 % environ d'halogénure de calcium, l'halogénure renfermant 0,3-0,6 % environ de bromure, et 99,4-99,7 % environ de chlorure. Ladite composition peut également contenir 0,05-0,2 % environ de sulfates, et 0,5-0,2 % de matières insolubles. Ces sels comprennent 34-38 % environ d'eau de cristallisation. La formulation d'aérosol selon l'invention, qui comprend de 0,5 environ à 5 environ grammes par litre d'une solution aqueuse stérile, ainsi qu'un tampon, est sensiblement exempte d'impuretés organiques nocives.

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