Microvesicles derived from recombinant yeast having...

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 17/04 (2006.01) A61K 9/14 (2006.01) A61P 7/04 (2006.01) C07K 14/745 (2006.01) C12N 15/09 (2006.01) C12N 15/81 (2006.01) C12P 21/02 (2006.01) A61K 38/36 (2006.01) C12N 1/19 (2006.01)

Patent

CA 2673996

Tissue factor-bearing yeast derived microvesicles comprising a yeast membrane and a tissue factor protein, or a fragment thereof, or a tissue factor protein or a fragment thereof fused to another peptide as a fusion protein having pro-coagulant activity are disclosed. Said products can be used as pro-coagulant agents in the treatment of hemorrhages in a subject.

L'invention concerne des microvésicules dérivées d'une levure portant un facteur tissulaire, qui comprennent une membrane de levure et une protéine de facteur tissulaire, ou un fragment de cette dernière, ou une protéine de facteur tissulaire ou un fragment de cette dernière fusionné à un autre peptide, comme protéine de fusion à activité procoagulante. Lesdits produits peuvent être utilisés comme agents procoagulants dans le traitement des hémorragies chez un sujet.

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