Tcl-5 gene rearrangement involved in t-cell leukemia and...

Details Tcl-5 gene rearrangement involved in t-cell leukemia and... Tcl-5 gene rearrangement involved in t-cell leukemia and...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C07H 21/04 (2006.01)

Patent

CA 2063409

2063409 9100364 PCTABS00003 A gene is described which is involved in the neoplastic process of a number of different cancers. The gene, termed TCL-5, is located at chromosome 1, band 32, adjacent to the chromosome junction formed during a t(1;14)(p32;q11) translocation. Probes and primers for detecting TCL-5 rearrangements are provided, as well as methods for detecting abnormalities in TCL-5 expression.

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