Direct fluorescence-conjugated immunoassay for platelet...

Details Direct fluorescence-conjugated immunoassay for platelet... Direct fluorescence-conjugated immunoassay for platelet...

G - Physics

01

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G01N 33/53 (2006.01) G01N 33/533 (2006.01) G01N 33/554 (2006.01) G01N 33/569 (2006.01) G01N 33/80 (2006.01) G01N 33/86 (2006.01)

Patent

CA 2184826

A method is provided to measure the extent of platelet activation by fluorometrically determining the extent of expression of P-selectin in a sample of whole blood in vivo, using a maximally activated platelet sample as a reference standard.

L'invention se rapporte à un procédé de mesure de l'étendue de l'activation plaquettaire qui consiste à déterminer par fluorimétrie in vitro l'étendue de l'expression de la sélectine P dans un échantillon de sang entier au moyen d'un échantillon de plaquettes activées au maximum, utilisé comme standard de référence.

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