Hair-growing composition

Details Hair-growing composition Hair-growing composition

A - Human Necessities

61

K

A61K 31/557 (2006.01) A61K 8/49 (2006.01) A61Q 7/00 (2006.01) A61K 7/06 (1990.01)

Patent

CA 2097278

A composition for stimulating hair growth is described. The composition comprises as an effective ingredient a 5,6,7-trinor-4,8-inter-m-phenylene prostaglandin I2 derivative of the formula (I) below or a pharmaceutically acceptable salt thereof: (see formula I) (wherein R1 represents hydrogen, carboxylic group or a functional derivative thereof, -CH2OH or a pharmaceutically acceptable cation; A represents (i) -(CH2)n-, (ii) -(CH2)m-CH=CH-(CH2)p-, (iii) -(CH2)m-C.ident.C-(CH2)p- or (iv) -CH2-O-CH2- (wherein n represents an integer of 0 - 3, m and p, the same or different, represent 0 or 1); -17- R2 represents (i) C5 - C10 straight or branched alkyl group, (ii) -C t H2t-OR3 (wherein t represents an integer of 1 - 5, R3 represents C1 - C5 straight or branched alkyl group or phenyl group), (iii) -C t H2t-CH=C(R4)(R5) (wherein t represents the same meaning as mentioned above, R4 and R5, the same or different, represent hydrogen, methyl, ethyl, propyl or butyl group), or (iv) -C t H2t-C.ident.C-R6 (wherein t represents the same meaning as mentioned above, R6 represents hydrogen, methyl or ethyl group, and -C t H2t in (ii), (iii) and (iv) represent straight or branched alkylene group); wherein said compound of the formula (I) may be d-, l- or dl-form.

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