Orally disintegrating composition comprising mirtazapine

Details Orally disintegrating composition comprising mirtazapine Orally disintegrating composition comprising mirtazapine

A - Human Necessities

61

K

A61K 31/55 (2006.01) A61K 9/00 (2006.01) A61K 9/20 (2006.01) A61K 9/46 (2006.01) A61K 9/50 (2006.01) A61P 25/24 (2006.01)

Patent

CA 2386547

New is an oral dosage unit comprising as an active ingredient the anti- depressant mirtazapine, wherein the dosage unit is of the orally- disintegrating type. The dosage unit, while rapidly disintegrating upon oral administration, is bioequivalent with conventional tablets, but can lead to advantages in terms of side-effects, efficacy, anxiolytic effects, sleep improving effects, and onset of action.

L'invention concerne une nouvelle forme galénique orale, comprenant en tant que principe actif l'antidépresseur mirtazapine, et conçue pour être du type à délitement oral. Cette forme galénique, à capacité rapide de délitement lors d'une administration orale, possède les mêmes effets biologiques que des comprimés classiques, mais elle peut induire des avantages par rapport à ceux-ci, notamment sous l'angle des effets secondaires, de l'efficacité, des effets anxiolytiques, de l'amélioration du sommeil et du début de son action.

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