Prevention and treatment of amyloidogenic disease

A - Human Necessities – 61 – K

Patent

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A61K 38/00 (2006.01) A61K 9/26 (2006.01) A61K 33/06 (2006.01) A61K 38/17 (2006.01) A61K 38/19 (2006.01) A61K 38/28 (2006.01) A61K 39/00 (2006.01) C07K 16/18 (2006.01)

Patent

CA 2312920

The invention provides compositions and methods for treatment of amyloidogenic diseases. Such methods entail administering an agent that induces a beneficial immune response against an amyloid deposit in the patient. The methods are particularly useful for prophylactic and therapeutic treatment of Alzheimer's disease. In such methods, a suitable agent is A.beta. peptide or an antibody thereto.

L'invention concerne des compositions et des procédés utiles pour le traitement de maladies amyloïdogènes. Ces procédés comportent l'administration d'un agent provoquant un réaction immunitaire bénéfique contre la formation d'un dépôt amyloïde chez le patient. Les procédés sont particulièrement utiles en vue d'un traitement prophylactique et thérapeutique de la maladie d'Alzheimer. Dans ces procédés, le peptide A.beta. ou un anticorps de celui-ci constitue un agent approprié.

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