Bicyclic indoline sulfonamide derivatives

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 209/08 (2006.01) A61K 31/404 (2006.01) A61P 3/04 (2006.01)

Patent

CA 2534171

The invention relates to novel bicyclic indoline sulfonamide derivatives of general formula (I), methods for the production thereof, and the use thereof in medicaments, especially as potent PPAR delta agonists for preventing and/or treating cardiovascular diseases, particularly dyslipidemia, arteriosclerosis, and coronary heart diseases.

La présente invention concerne de nouveaux dérivés bicycliques d'indoline-sulfonamides de formule générale (I), des procédés de production de ces composés et l'utilisation desdits composés dans des médicaments, en particulier comme activateurs puissants de PPAR delta pour la prévention et/ou le traitement de maladies cardiovasculaires, notamment la dyslipidémie, l'artériosclérose et les maladies coronariennes.

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