Least damaging treatments for antibiotic bacteria/viruses (&...

A - Human Necessities – 61 – K

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A61K 45/06 (2006.01) A61K 51/12 (2006.01) A61P 31/00 (2006.01)

Patent

CA 2587110

In addition to the localized multi needles of number, shape, lengths and sizes we could: 1. Perhaps use magnetized particles in the nano shells/or retro virus/ or bis peptides or combination to move a solution/swarm of these particles toward the concentration of the infection or where the infection is most virulent and stubborn and most importantly where it is starting to infect a critical organ, eg. hemorrhagic fever. 2. Use radio active particles to track the position of the swarm/solution (of nano shells or retro viruses or bis peptides or combination) spread/concentration to know when (guesstimate) is best to electrically stimulate. 3. Then when the (i) nano shells or retro viruses or bis peptides or combination are next to or bonded/linked/connected to the protein or other mechanism on the cell membrane of the (ii) antibiotic resistant/or virulent bacteria/virus, we could use electrical stimulus to cause (i) to fuse into (ii). 4. Finally we could create a bis peptide that carries (linked/connected/bonded) on one end to nano shells and/or retro viruses (possibly multiple), and on the other end (amine/carboxyl)s specifically designed to bond/link/connect to the antibiotic resistant or virulent bacteria/virus but not to affect any human cells. 5. We could use epigenetic drugs (molecular switches) such as methylation to turn off the genes (or other organism parts) responsible for the increase in antibiotic resistance and also virulence. Or perhaps acetylation, which might turn on the gene to be antibiotic resistant. Whichever works. We prefer this treatment because it is less invasive, after our solution/swarm has delivered the epigenetic drugs to take away the antibiotic resistance and or virulence, we can administer less strong versions of antibiotics and end the eternal war to out evolve the ever growing resisrance of bacteria/viruses to resistance. 6. We could design nano shell decoys (to have a similar surface as human cells - study what mechanism the specifically viruses but also bacteria - activate their attack instincts; attracts them to seek and infect human cells). Or retro virus and or nano shells and or bis peptide decoys that either fills up their binding site or when attacked, and or deliver epigenetic drug - a chemical that is lethal (perhaps disabling key survival bacteria/virus parts - that does not necessarily affect the bacteria/viruses outer cell membrane so the chemical does affect the human patient's body) to the antibiotic resistant/virulent bacteria/virus, but this chemical if spills outside the bacteria/virus membrane would be dissolved/dispersed into harmless concentration.

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