Treatment of soft tissue to increase porosity

Details Treatment of soft tissue to increase porosity Treatment of soft tissue to increase porosity

A - Human Necessities

01

N

A01N 1/02 (2006.01) A61F 2/10 (2006.01)

Patent

CA 2677305

The present invention relates to a process for treating a decellularized soft tissue such as dermis by freezing the same at a plurality of decreasing temperatures at atmosphere or higher to cause the formation of ice crystals having a size greater than 2.0µ and lyophilizing the soft tissue under vacuum to remove the water to less than 6%forming a porous matrix.

La présente invention concerne un procédé de traitement d'un tissu mou décellularisé tel que le derme en le congelant à une pluralité de températures décroissantes à pression atmosphérique ou supérieure pour entraîner la formation de cristaux de glace ayant une taille supérieure à 2,0 µ et en lyophilisant le tissu mou sous vide pour enlever l'eau à moins de 6 %, formant une matrice poreuse.

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