Method for diagnosing diffuse-type gastric cancer

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01)

Patent

CA 2503517

Methods for detecting and diagnosing diffuse-type gastric cancer (DGC) are described herein. In one embodiment, the diagnostic method involves the determination of an expression level of DGC -associated gene that discriminate between DGC and normal cell. The present invention further provides methods of screening for therapeutic agents useful in the treatment of DGC, methods of treating DGC and method of vaccinating a subject against DGC.

La présente invention concerne des méthodes de détection et de diagnostic de cancers gastriques de type diffus (DGC). Selon un mode de réalisation, la méthode de diagnostic implique la détermination d'un niveau d'expression d'un gène associé aux DGC qui diffère entre une cellule de DGC et une cellule normale. La présente invention concerne également des méthodes de criblage d'agents thérapeutiques utiles dans le traitement de DGC, des méthodes de traitement de DGC et une méthode de vaccination d'un sujet contre des DGC.

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