Methods and kits for determining blood coagulation

Details Methods and kits for determining blood coagulation Methods and kits for determining blood coagulation

G - Physics

01

N

G01N 33/49 (2006.01) G01N 33/86 (2006.01)

Patent

CA 2640167

A method of determining a coagulation status of a blood sample is provided. The method comprising determining an expression and/or activity ratio of Tissue Factor (TF) to Tissue Factor Pathway Inhibitor (TFPI) in cellular microparticles of the blood sample, wherein the ratio is indicative of the coagulation status of the blood sample.

La présente invention concerne un procédé pour évaluer l'état de coagulation d'un échantillon sanguin. Ce procédé consiste à déterminer un rapport d'expression et/ou d'activité entre le facteur TF (Tissue Factor) et l'inhibiteur TFPI (Tissue Factor Pathway Inhibitor) dans des microparticules cellulaires de l'échantillon sanguin, ce rapport fournissant une indication de l'état de coagulation de l'échantillon sanguin.

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