C - Chemistry – Metallurgy – 07 – F
Patent
C - Chemistry, Metallurgy
07
F
C07F 9/655 (2006.01) A61K 31/665 (2006.01) C07F 9/6558 (2006.01)
Patent
CA 2585353
Phosphorus substituted mycophenolate oxime derivatives with anti-cancer, anti- viral, anti-inflammatory and anti-tissue/organ transplant rejection properties having use as therapeutics and for other industrial purposes are disclosed. The compositions inhibit tumor growth, viral growth, inflammation, and tissue/organ transplant rejection and/or are useful therapeutically for the treatment or prevention of cancer, viral infection, inflammation and tissue/organ transplant rejection, as well as in assays for the detection of cancer, viral infection, inflammation and tissue/organ transplant rejection.
L'invention concerne des dérivés de mycophenolate oxime de phosphore substitués qui possèdent des propriétés anticancéreuses, antivirales, anti-inflammatoires et anti-rejet de greffes de tissus/organes, et qui, en plus de leur utilisation industrielle, servent d'agents thérapeutiques. Ces compositions empêchent la croissance tumorale, la multiplication des virus, l'inflammation, le rejet de greffes de tissus/organes et/ou servent d'agent thérapeutiques dans le traitement ou la prévention du cancer, de l'infection virale, de l'inflammation et du rejet de greffes de tissus/organes, ainsi que dans des dosages de dépistage du cancer, de l'infection virale, de l'inflammation et du rejet de greffes de tissus/organes.
Cho Aesop
Watkins William J.
Gilead Sciences Inc.
Robic
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