C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/10 (2006.01) A61K 38/16 (2006.01) A61K 38/17 (2006.01) A61K 38/18 (2006.01) A61K 38/19 (2006.01) C07K 14/47 (2006.01) C07K 14/475 (2006.01) C07K 14/48 (2006.01) C07K 16/18 (2006.01) C07K 16/22 (2006.01) C12N 15/12 (2006.01) C12N 15/16 (2006.01) C12N 15/63 (2006.01) C12N 15/64 (2006.01)
Patent
CA 2395763
The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted semaphorin-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from fetal liver-spleen (Hyseq clone identification numbers 5688868 (SEQ ID NO: 1)). Other aspects of the invention include vectors containing processes for producing novel human secreted semaphorin-like polypeptides, and antibodies specific for such polypeptides.
Cette invention se rapporte à de nouveaux polynucléotides et à des polypeptides codés par ces polynucléotides et à des mutants ou variants de ceux-ci, qui correspondent à un nouveau polypeptide de type sémaphorine sécrété humain. Ces polynucléotides comprennent des séquences d'acide nucléique isolées à partir d'une bibliothèque d'ADNc provenant du foie/de la rate d'un foetus (numéros d'identification de clones Hyseq 5688868 (SEQ ID:1)). D'autres aspects de cette invention concernent des vecteurs contentant des processus pour produire de nouveaux polypeptides de type sémaphorine sécrétés humains, et des anticorps spécifiques de ces polypeptides.
Arterburn Matthew C.
Boyle Bryan J.
Drmanac Radoje T.
Liu Chenghua
Mize Nancy K.
Hyseq Inc.
Nuvelo Inc.
Smart & Biggar
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