Method for detection of promoter methylation status

Details Method for detection of promoter methylation status Method for detection of promoter methylation status

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01)

Patent

CA 2555704

The present invention relates to the detection of promoter methylation status using a combination of either modification of methylated DNA or restriction endonuclease digestion, multiplex polymerase chain reaction, ligase detection reaction, and a universal array or capillary electrophoresis detection.

La présente invention a trait à la détection d'état de méthylation de promoteur au moyen d'une combinaison de soit la modification d'ADN méthylé ou de digestion d'endonucléase de restriction, de la réaction en chaîne de la polymérase en multiplexe, de la réaction de détection de ligase, et la détection d'un réseau universel ou d'électrophorèse capillaire.

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