C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/34 (2006.01) A61K 31/00 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01) A61P 9/00 (2006.01) C07K 16/40 (2006.01) C12N 9/16 (2006.01)
Patent
CA 2521303
The present invention provides the use of PDE4, preferably PDE4D, more preferably PDE4D5 or PDE4D7, as a novel target for the identification of compounds that can be used for the treatment of atherosclerosis, preferably of Peripheral Arterial Occlusive Disease (PAOD), or for the treatment of restenosis.
L'invention concerne l'utilisation de PDE4, de préférence PDE4D, idéalement de PDE4D5 ou PDE4D7, comme nouvelle cible pour l'identification de composés pouvant être utilisés pour le traitement de l'athérosclérose, de préférence, de la maladie artérielle occlusive périphérique (PAOD) ou de la resténose.
Evers Stefan
Fingerle Juergen
Gretarsdottir Solveig
Gulcher Jeffrey R.
Himber Jacques
Decode Genetics Ehf.
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
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