Methods and compositions for identifying gene function

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01) C12N 15/10 (2006.01)

Patent

CA 2441209

The present invention relates to methods and compositions for the efficient identification of one or more functionalities of a product encoded by a nucleic acid sequence of interest. The methods utilize the abilities to over and/or under express the product in a cell, as well as the combination of these results, to permit the identification of at least one of the product's cellular orin vivo functionality.

L'invention concerne des procédés et des compositions servant à identifier efficacement une ou plusieurs fonctions d'un produit codé par une séquence définie d'acide nucléique. Ces procédés mettent en application les capacités de surexpression et/ou sous-expression du produit dans une cellule, ainsi que la combinaison de ces résultats, de manière à permettre l'identification d'au moins une des fonctions cellulaires ou in vivo de ce produit.

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