Surface modified nsaid nanoparticles

Details Surface modified nsaid nanoparticles Surface modified nsaid nanoparticles

A - Human Necessities

61

K

A61K 9/14 (2006.01)

Patent

CA 2118517

Dispersible particles consisting essentially of a crystalline NSAID having a surface modifier adsorbed on the surface thereof in an amount sufficient to maintain an effective average particle size of less than about 400 nm. Pharmaceutical composi- tions containing the particles exhibit reduced gastric irritation following oral administration and/or hastened onset of action.

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