Tumor antigen protein, gene thereof, and utilization thereof

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 31/70 (2006.01) C07K 14/47 (2006.01) C07K 14/82 (2006.01) C07K 16/32 (2006.01) C12N 5/10 (2006.01) G01N 33/563 (2006.01) A61K 38/00 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2316396

A DNA comprising the base sequence represented by SEQ ID NO:1 or a DNA hybridizing with a DNA comprising the base sequence represented by SEQ ID NO:1 under stringent conditions and encoding a protein having activities as a tumor antigen; an expression plasmid bearing the above DNA; a product of transformation therewith; a tumor antigen protein produced as a result of expression of the above DNA; an antibody against the above protein; and the utilization thereof for the remedy, prevention or diagnosis of tumors.

L'invention concerne un ADN comprenant la séquence de bases représentée par SEQ ID NO 1 ou un ADN s'hybridant avec un ADN comprenant la séquence de bases représentée par SEQ ID NO 1 dans des conditions sévères et codant une protéine possédant des activités d'antigène tumoral; un plasmide d'expression servant de support à l'ADN ci-dessus; un produit de sa transformation; une protéine d'antigène tumoral produite comme le résultat de l'expression de l'ADN ci-dessus; un anticorps contre la protéine ci-dessus; et son utilisation pour le traitement, la prévention et le diagnostic de tumeurs.

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