Helicobacter pylori antigens and vaccine compositions

Details Helicobacter pylori antigens and vaccine compositions Helicobacter pylori antigens and vaccine compositions

C - Chemistry, Metallurgy

12

N

C12N 15/31 (2006.01) A61K 39/106 (2006.01) C07K 14/205 (2006.01) G01N 33/543 (2006.01) G01N 33/569 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2222797

The present invention relates to recombinant polypeptides which constitute Helicobacter pylori surface-exposed antigens with an approximate molecular weight of 29 kDa. The invention furthermore provides nucleic acid molecules coding for the said polypeptides, as well as vectors and host cells comprising such nucleic acid molecules. The said recombinant polypeptides are useful for the diagnosis of H. pylori infections and for the manufacture of vaccine compositions which will elicit a protective immune response against such infections, said vaccine compositions being suitble for both therapeutic and prophylactic use.

La présente invention concerne des polypeptides de recombinaison qui constituent des antigènes exposés sur la surface des Helicobacter pylori avec un poids moléculaire d'environ 29 kDa. L'invention concerne aussi des molécules d'acide nucléique codant pour ces polypeptides, ainsi que des vecteurs et des cellules hôtes comprenant ces molécules d'acides nucléiques. Ces polypeptides de recombinaison permettent de diagnostiquer les infections par H. Pylori et de fabriquer des compositions de vaccins qui induisent une réponse de protection immunitaire contre ces infections. Ces compositions se prêtent à des applications thérapeutiques et prophylactiques.

Affiliated with

Also associated with

Rating

Helicobacter pylori antigens and vaccine compositions does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Helicobacter pylori antigens and vaccine compositions, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Helicobacter pylori antigens and vaccine compositions will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1631255