Modified protease inhibitors

Details Modified protease inhibitors Modified protease inhibitors

A - Human Necessities

61

K

A61K 38/00 (2006.01) C07K 14/00 (2006.01) C12N 9/00 (2006.01) C12N 9/66 (2006.01)

Patent

CA 2537113

DX-890 inhibits elastase. DX-890 can be attached a single polyethylene glycol moiety. The polyethylene glycol is at least 18 kDa in molecular weight and is attached to the polypeptide by a single covalent bond to the N-terminus of the polypeptide.

L'invention concerne un composé DX-890 qui inhibe l'élastase. DX-890 peut être fixé à une seule fraction polyéthylène glycol. Le polyéthylène glycol, qui est d'un poids moléculaire de 18 kDa, est fixé au polypeptide au moyen d'une seule liaison covalente au N-terminal du polypeptide.

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